Recombinant human CYP8B1 protein, Unconjugated

Product Overview

• Article Name: Recombinant human CYP8B1 protein, Unconjugated
• Biozol Catalog Number: BSS-BS-42311P
• Supplier Catalog Number: bs-42311P
• Alternative Catalog Number: BSS-BS-42311P-100,BSS-BS-42311P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]

Product Properties

• Tag: N-His
• NCBI: 1582
• UniProt: Q9UNU6
• Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea and 0.5M L-Arg.
• Source: Recombinant human CYP8B1 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 22-501/501
• Expression System: E.coli
• Purity: > 90% as determined by SDS- PAGE