Recombinant human PDGFRB protein, N-Trx-His, Unconjugated
Catalog Number:
BSS-BS-42312P
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| Article Name: | Recombinant human PDGFRB protein, N-Trx-His, Unconjugated |
| Biozol Catalog Number: | BSS-BS-42312P |
| Supplier Catalog Number: | bs-42312P |
| Alternative Catalog Number: | BSS-BS-42312P-20,BSS-BS-42312P-100,BSS-BS-42312P-500 |
| Manufacturer: | Bioss |
| Category: | Proteine/Peptide |
| Species Reactivity: | Other |
| Conjugation: | Unconjugated |
| This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq]. |
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