Recombinant human CXADR Protein, N-His, Unconjugated

Product Overview

• Article Name: Recombinant human CXADR Protein, N-His, Unconjugated
• Biozol Catalog Number: BSS-BS-42449P
• Supplier Catalog Number: bs-42449P
• Alternative Catalog Number: BSS-BS-42449P-100,BSS-BS-42449P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

Coxsackie and adenovirus receptor (CAR), also known as CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity. It is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.It is proposed to function as a homophilic cell adhesion molecule and recruits MPDZ to intercellular contact sites. CAR is probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN) through adhesive interactions with AMICA1/JAML located in the plasma membrane of PMN.

Product Properties

• Tag: N-His
• NCBI: 1525
• UniProt: P78310
• Buffer: 20mM Tris-Hcl (pH=8.0) with 8M Urea.
• Source: Recombinant human CXADR Protein in E.coli with N-His. It contains the amino acid sequence of 20-237/365
• Expression System: E.coli
• Purity: > 90% as determined by SDS- PAGE