phospho-IRE1a (Ser 726) Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit

Product Overview

• Article Name: phospho-IRE1a (Ser 726) Polyclonal Antibody, AbBy Fluor-488 Conjugated, BF488, Rabbit
• Biozol Catalog Number: BSS-BS-4308R-BF488
• Supplier Catalog Number: bs-4308R-BF488
• Alternative Catalog Number: BSS-BS-4308R-BF488-100,BSS-BS-4308R-BF488-20
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, IF, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: BF488
• Alternative Names: IRE1, IRE1P, IRE1a, hIRE1p, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, ERN1

Product Description

Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 2081
• UniProt: O75460
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human IRE1a around the phosphorylation site of Ser 726
• Purity: Purified by Protein A.
• Target: phospho-IRE1a (Ser 726)

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)