Recombinant human SHBG protein (HEK293), His, Unconjugated

Product Overview

• Article Name: Recombinant human SHBG protein (HEK293), His, Unconjugated
• Biozol Catalog Number: BSS-BS-43202P
• Supplier Catalog Number: bs-43202P
• Alternative Catalog Number: BSS-BS-43202P-20,BSS-BS-43202P-100,BSS-BS-43202P-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Species Reactivity: Other
• Conjugation: Unconjugated

Product Description

Sex hormone binding globulin (SHBG) is a glycoprotein synthesized by the liver. Circulating androgen and estrogen concentrations influence SHBG synthesis. Elevated testosterone, for example, causes SHBG synthesis to decrease, whereas high estrogen stimulates SHBG production. The regulation of SHBG synthesis, combined with SHBGs higher affinity for testosterone, impacts bioavailable testosterone levels. SHBG binds up to 98 percent of the steroid hormones in the blood including 5a-dihydrotestosterone (DHT), testosterone and androstenediol with particularly high affinity, and estradiol and estrone with slightly lower affinity.

Product Properties

• Tag: C-His
• NCBI: 6462
• UniProt: P04278
• Buffer: 0.01M TBS(pH7.4)
• Source: Recombinant human SHBG protein (HEK293) is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 30-402/402
• Expression System: HEK293
• Purity: > 90% as determined by SDS- PAGE