Adipocyte dferentiation inhibitor protein, Brevideltin, Delta like 1 homolog, Delta like homolog, Delta like protein, Delta1, DLK 1, DLK, DLK-1, Dlk1, DLK1_HUMAN, FA 1, FA1, Fetal antigen 1, pG2, Preadipocyte factor 1, Pref 1, Pref, Pref1, Pref-1, Protein delta homolog 1, Secredeltin, ZOG, Delta1, PREF1.
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes, it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].
Clonality:
Polyclonal
Concentration:
1ug/ul
Buffer:
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source:
KLH conjugated synthetic peptide derived from sheep DLK1
Target:
DLK1
Application Dilute:
WB(WB=1:500-2000), IF(IF=1:100-500)
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