PPAR Gamma Polyclonal Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-4590R-PE
Supplier Catalog Number:
bs-4590R-PE
Alternative Catalog Number:
BSS-BS-4590R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
FC, IF, WB
Species Reactivity:
Human, Mouse, Rat
Conjugation:
PE
Alternative Names:
GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma, Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, PPARG
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity).
