A new variant of SARS-CoV-2 is spreading in the UK and is rapidly becoming a global threat. It is characterized by multiple mutations in the spike protein. Among them, N501Y is of major concern because it involves one of the six key amino acid residues determining a tight interaction of the SARS-CoV-2 receptor-binding domain (RBD) with its cellular receptor angiotensin-converting enzyme 2 (ACE2).
Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
Source:
Recombinant SARS-COV-2 Spike S1 (N501Y) Protein protein is expressed in HEK293 with His tag. It contains the amino acid sequence of Val16-Arg685 (N501Y).
Expression System:
HEK293
Purity:
> 95% as determined by Bis-Tris PAGE, > 95% as determined by HPLC
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