Recombinant Human ACE2 Protein, Biotin Conjugated

Product Overview

• Article Name: Recombinant Human ACE2 Protein, Biotin Conjugated
• Biozol Catalog Number: BSS-BS-46110P-BIOTIN
• Supplier Catalog Number: bs-46110P-Biotin
• Alternative Catalog Number: BSS-BS-46110P-BIOTIN-20,BSS-BS-46110P-BIOTIN-100,BSS-BS-46110P-BIOTIN-500
• Manufacturer: Bioss
• Category: Proteine/Peptide
• Application: ELISA, WB
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, and heart, in the colon, small intestine, and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor, don,Aot inhibit ACE-2 activity. ACE-2 may play an essential role in regulating heart function.

Product Properties

• Tag: C-His
• NCBI: 001358344
• UniProt: Q9BYF1
• Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
• Source: Recombinant Human ACE2 Protein protein is expressed in Mammalian cells with C-His. It contains the amino acid sequence of Met1-Ser740.
• Expression System: Mammalian cells
• Purity: >95% as determined by SDS-PAGE