AC133, Antigen AC133, Hematopoietic stem cell antigen, hProminin, PROM1, Prominin I, Prominin 1, Prominin1, Prominin-1, Prominin like protein 1 precursor, Prominin mouse like 1, prominin1, PROML1, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4.
May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
