CD45 Polyclonal Antibody, Unconjugated, Rabbit

Catalog Number: BSS-BS-4819R
Article Name: CD45 Polyclonal Antibody, Unconjugated, Rabbit
Biozol Catalog Number: BSS-BS-4819R
Supplier Catalog Number: bs-4819R
Alternative Catalog Number: BSS-BS-4819R-100
Manufacturer: Bioss
Host: Rabbit
Category: Antikörper
Application: ELISA, IF, IHC-Fr, IHC-P, WB
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: Lca, RT7, CD45, L-CA, T200, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, Ptprc
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Clonality: Polyclonal
Concentration: 1ug/ul
NCBI: 24699
Pubmed: 25329797
UniProt: P04157
Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source: KLH conjugated synthetic peptide derived from rat CD45
Target: CD45
Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200)