5-hmC Monoclonal Antibody(mouse), IgG1, Unconjugated, Mouse

Product Overview

• Article Name: 5-hmC Monoclonal Antibody(mouse), IgG1, Unconjugated, Mouse
• Biozol Catalog Number: BSS-BS-51025R
• Supplier Catalog Number: bs-51025R
• Alternative Catalog Number: BSS-BS-51025R-50
• Manufacturer: Bioss
• Host: Mouse
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: ORC2L, Origin recognition complex subunit 2, ORC2

Product Description

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.

Product Properties

• Clonality: Monoclonal
• Concentration: 0.6ug/ul
• Isotype: IgG1
• NCBI: 4999
• UniProt: Q13416
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively
• Target: ORC2

Application Notes

• Application Dilute: WB(1:300-5000)