phospho-Caspase 6 (Ser257) Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: phospho-Caspase 6 (Ser257) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-5240R-BIOTIN
• Supplier Catalog Number: bs-5240R-Biotin
• Alternative Catalog Number: BSS-BS-5240R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, WB
• Species Reactivity: Mouse
• Conjugation: Biotin
• Alternative Names: Apoptosis-related cysteine protein, Apoptosis Related Cysteine Protease, Apoptotic cysteine protease MCH2, Apoptotic protease MCH 2, Apoptotic protease MCH2, Casp 6, Casp6, Caspase 6 apoptosis related cysteine protease, Caspase 6 precursor, Caspase6, Human cysteine protease Mch2 isoform alpha, Mch 2, Mch2, CASP6_HUMAN.

Product Description

Caspase-6 is involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 839
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human Caspase 6 around the phosphorylation site of Ser257
• Target: phospho-Caspase 6 (Ser257)

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-F(1:100-500)