Phospho-Caspase-9 (Ser196) Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit

Product Overview

• Article Name: Phospho-Caspase-9 (Ser196) Polyclonal Antibody, PE-Cy7 Conjugated, PE/Cy7, Rabbit
• Biozol Catalog Number: BSS-BS-5241R-PE-CY7
• Supplier Catalog Number: bs-5241R-PE-Cy7
• Alternative Catalog Number: BSS-BS-5241R-PE-CY7-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: PE/Cy7
• Alternative Names: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP9

Product Description

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 842
• UniProt: P55211
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human CASP9 around the phosphorylation site of Ser196
• Target: Phospho-Caspase-9 (Ser196)

Application Notes

• Application Dilute: WB(1:300-5000)