phospho-Cdc25B (Ser186) Polyclonal Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: phospho-Cdc25B (Ser186) Polyclonal Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BS-5244R
• Supplier Catalog Number: bs-5244R
• Alternative Catalog Number: BSS-BS-5244R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC-Fr, IHC-P, WB
• Species Reactivity: Mouse
• Conjugation: Unconjugated
• Alternative Names: M-phase inducer phosphatase 2, Dual specificity phosphatase Cdc25B, CDC25B, CDC25HU2

Product Description

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 994
• UniProt: P30305
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human Cdc25B around the phosphorylation site of Ser186
• Target: phospho-Cdc25B (Ser186)

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)