Parkin (Ser378) Antibody, Unconjugated, Rabbit, Polyclonal
Catalog Number:
BSS-BS-70217R
Product Overview
Article Name:
Parkin (Ser378) Antibody, Unconjugated, Rabbit, Polyclonal
Biozol Catalog Number:
BSS-BS-70217R
Supplier Catalog Number:
bs-70217R
Alternative Catalog Number:
BSS-BS-70217R-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human
Conjugation:
Unconjugated
Alternative Names:
AR JP antibody, E3 ubiquitin ligase antibody, E3 ubiquitin protein ligase parkin antibody, E3 ubiquitin-protein ligase parkin antibody, FRA6E antibody, LPRS 2 antibody, LPRS2 antibody, PARK 2 antibody, Park2 antibody, Parkin 2 antibody, Parkinson disease (autosomal recessive juvenile) 2 antibody, Parkinson disease (autosomal recessive juvenile) 2 parkin antibody, Parkinson disease protein 2 antibody, Parkinson juvenile disease protein 2 antibody, Parkinson protein 2 E3 ubiquitin protein ligase antibody, Parkinson protein 2 E3 ubiquitin protein ligase (parkin) antibody, PDJ antibody, PRKN 2 antibody, PRKN antibody, PRKN2 antibody, PRKN2_HUMAN antibody, Ubiquitin E3 ligase PRKN antibody
Product Description
Parkin is an E3 ligase in the ubiquitin-proteasome system. Hereditary Parkinsons disease is most commonly caused by mutations in the parkin gene and is characterized by the progressive loss of dopaminergic neurons and the presence of Lewy bodies in the substantia nigra (Jenner et al.,1992). Recent evidence suggests that phosphorylation of parkin at Ser-378 may have an important regulatory role on its E3 ubiquitin ligase activity (Yamamoto et al., 2005).
Product Properties
Clonality:
Polyclonal
Concentration:
Lot Dependent
NCBI:
5071
UniProt:
O60260
Buffer:
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Source:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser378 of human Parkin, conjugated to keyhole limpet hemocyanin (KLH).
Purity:
Antigen Affinity purification from Pooled whole antiserum
Target:
Parkin (Ser378)
Antibody Type:
Primary Antibody
Application Notes
Application Dilute:
WB(1:300-5000)
