Inhibitor of p53 induced apoptosis beta, IPIA beta, NDK-H 5, NDP kinase homolog 5, NM23 H5, Nm23-M5, NM23H5, Non-metastatic cells 5, protein expressed in nucleoside-diphosphate kinase, Nonmetastatic cells 5, protein expressed in, Nonmetastatic protein 23, homolog 5, Nucleoside diphosphate kinase homolog 5, RSPH23, Testis specic nm23 homolog, NDK5_HUMAN.
NME5 does not seem to have NDK kinase activity but confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. It may play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. NME5 is specifically expressed in testis germinal cells.
