Faim3,FAIM3_HUMAN,Fas apoptotic inhibitory molecule 3,Fc mu receptor,R,IgM Fc receptor,Immunoglobulin mu Fc receptor,Regulator of Fas induced apoptosis,Regulator of Fas-induced apoptosis Toso,TOSO.
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.Tissue specificity: Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland.
Clonality:
Polyclonal
Concentration:
1ug/ul
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source:
KLH conjugated synthetic peptide derived from human FAIM3
