Oxaliplatin, CAS [[61825-94-3]], Unconjugated
Catalog Number:
BSS-BS-75501C
| Article Name: |
Oxaliplatin, CAS [[61825-94-3]], Unconjugated |
| Biozol Catalog Number: |
BSS-BS-75501C |
| Supplier Catalog Number: |
bs-75501C |
| Alternative Catalog Number: |
BSS-BS-75501C-5,BSS-BS-75501C-25,BSS-BS-75501C-100 |
| Manufacturer: |
Bioss |
| Category: |
Biochemikalien |
| Conjugation: |
Unconjugated |
| Potent platinum-based antineoplastic agent with wide spectrum anticancer activity [2, 7-9]. Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death [1, 4, 7, 10, 13]. Shows antitumor activity in cisplatin resistant cell lines [3, 8]. Shows better biochemical, pharmacological and cytotoxic properties than cisplatin (Prod. No. bs-75499C) and carboplatin (Prod. No. bs-75500C) [5, 7, 8]. Apoptosis inducer [10, 11]. Targets other proteins and enzymes [6]. Anticancer activity and antitumor specificity depends on selective uptake through human organic cation transporters 1 (OCT1) and OCT2 [12]. Neurotoxic profile depends on organic cation transporter 2 (OCT2) uptake [14]. |
| Buffer: |
Powder |
| CAS Number: |
[61825-94-3] |
