CK2 Inhibitor 10, CAS [[1361229-76-6]], Unconjugated

Product Overview

• Article Name: CK2 Inhibitor 10, CAS [[1361229-76-6]], Unconjugated
• Biozol Catalog Number: BSS-BS-75525C
• Supplier Catalog Number: bs-75525C
• Alternative Catalog Number: BSS-BS-75525C-1,BSS-BS-75525C-5
• Manufacturer: Bioss
• Category: Biochemikalien
• Conjugation: Unconjugated

Product Description

Potent and ATP-competitive inhibitor of casein kinase 2 (IC50 CK2alpha=32nM and IC50 CK2alpha=46nM). Potently also inhibits DYRK1B and FLT3. Anticancer compound. Exhibits potent cytotoxicity towards lung cancer cells A549, colorectal cancer cells HCT-116 and breast cancer cells MCF-7. Promoted cAMP-induced thermogenesis in white adipocytes. CK2 inhibition ameliorates diet-induced obesity and insulin resistance in mice in vivo by promoting UCP1-dependent thermogenesis.

Product Properties

• Buffer: Solid
• CAS Number: [1361229-76-6]