VHL Polyclonal Antibody, AbBy Fluor-680 Conjugated, BF680, Rabbit

Product Overview

• Article Name: VHL Polyclonal Antibody, AbBy Fluor-680 Conjugated, BF680, Rabbit
• Biozol Catalog Number: BSS-BS-7883R-BF680
• Supplier Catalog Number: bs-7883R-BF680
• Alternative Catalog Number: BSS-BS-7883R-BF680-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Species Reactivity: Mouse, Rat
• Conjugation: BF680
• Alternative Names: pVHL, pVHL, G7 protein, Elongin binding protein, HRCA 1, HRCA1, Protein G7, pVHL, RCA 1, RCA1, VHL 1, VHL, VHL_HUMAN, VHL1, VHLH, Von Hippel Lindau disease tumor suppressor, von Hippel Lindau syndrome, von Hippel Lindau tumor suppressor, Von Hippel-Lindau disease tumor suppressor.

Product Description

Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 7428
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human VHLH/Von Hippel Lindau
• Target: VHL

Application Notes

• Application Dilute: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)