DUSP26 Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: DUSP26 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-7910R-BIOTIN
• Supplier Catalog Number: bs-7910R-Biotin
• Alternative Catalog Number: BSS-BS-7910R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-Fr, IHC-P, WB
• Species Reactivity: Human, Rat
• Conjugation: Biotin
• Alternative Names: DSP-4, Dual specicity phosphatase 26 putative, Dual specicity phosphatase 26, Dual specicity phosphatase SKRP3, Dual specicity protein phosphatase 26, DUS26_HUMAN, DUSP24, DUSP26, Hypothetical protein FLJ31142, LDP 4, LDP-4, Low molecular mass dual specicity phosphatase 4, Low-molecular-mass dual-specicity phosphatase 4, MAP kinase phosphatase 8, MGC1136, MGC2627, Mitogen activated protein kinase phosphatase 8, Mitogen-activated protein kinase phosphatase 8, MKP-8, MKP8, NATA1, NATA1 protein, Novel amplied gene in thyroid anaplastic cancer, SKRP3.

Product Description

Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).Tissue specificity:Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human DUSP26/MKP8
• Target: DUSP26

Application Notes

• Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)