Phospho-TrkA (Tyr791) Polyclonal Antibody, RBITC Conjugated, Rabbit

Product Overview

• Article Name: Phospho-TrkA (Tyr791) Polyclonal Antibody, RBITC Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-8456R-RBITC
• Supplier Catalog Number: bs-8456R-RBITC
• Alternative Catalog Number: BSS-BS-8456R-RBITC-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Species Reactivity: Human
• Conjugation: RBITC
• Alternative Names: TrkA Tyr791, TrkA Phospho Tyr791, TrkA Y791, p-TrkATyr791, CIPA, CIPA, DKFZp781I14186, gp140trk, High affinity nerve growth factor receptor, High affinity nerve growth factor receptor precursor, High affinity nerve growth factor receptor precursor, MTC, MTC, neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase receptor type 1, Ntrk 1, Ntrk1, Ntrk1, NTRK1_HUMAN, Oncogene TRK, Oncogene TRK, p140 TrkA, p140-TrkA, TRK 1, Trk A, TRK, TRK, Trk-A, TRK1, TRK1 transforming tyrosine kinase protein, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor A, Tyrosine kinase receptor, Tyrosine Receptor Kinase A.

Product Description

The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140),Trk B and Trk C. The prototype member of this gene family, Trk A, encodes a 140 kDa cell surface receptor , gp140, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia. By comparison, BDNF and to a lesser extent, NT-3, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145. The third member of the Trk receptor family, Trk C incodes a 140 kDa protein, Trk C gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3.An additional component of the Trk receptor complex, NGFR p175, binds to neurotrophic factors with low affinity but is required for efficient signaling. NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 4914
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human TrkA around the phosphorylation site of Tyr791
• Purity: Purified by Protein A.
• Target: Phospho-TrkA (Tyr791)
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)