TSPAN13 Polyclonal Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-9421R-PE
Supplier Catalog Number:
bs-9421R-PE
Alternative Catalog Number:
BSS-BS-9421R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
IF
Species Reactivity:
Human, Mouse, Rat
Conjugation:
PE
Alternative Names:
NET 6, NET6, Tetraspan NET-6, Tetraspanin-13, TM4SF13, Transmembrane 4 superfamily member 13, Transmembrane 4 superfamily member tetraspan NET 6, Tspan-13, Tspan13, TSN13_HUMAN.
NET-6, also known as TSPAN13 (tetraspanin-13) or TM4SF13 (transmembrane 4 superfamily member 13), is a 204 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission. The gene encoding NET-6 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
