C21orf14, C21orf38, C21orf7, Chromosome 21 open reading frame 38, Chromosome 21 open reading frame 91, Early undferentiated retina and lens, EURL, Protein EURL homolog, YG81, TSEAR_HUMAN.
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.
Clonality:
Polyclonal
Concentration:
1ug/ul
Buffer:
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source:
KLH conjugated synthetic peptide derived from human TSPEAR/C21orf9
Target:
TSPEAR
Application Dilute:
WB(WB=1:500-2000), IF(IF=1:100-500)
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