Alpha-synuclein (nitro-Tyr39) Polyclonal Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Alpha-synuclein (nitro-Tyr39) Polyclonal Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BS-9587R
• Supplier Catalog Number: bs-9587R
• Alternative Catalog Number: BSS-BS-9587R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, IF, IHC-Fr, IHC-P
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: SYUA_HUMAN, nitrated Alpha-synuclein nitrated-Tyr39, nitrated Alpha-synuclein nitro-Tyr39, Alpha-synuclein nitro-Tyr39, Alpha-synuclein nitro Tyr39, nitrated Alpha synuclein, nitrated Alpha-Synuclein, Alpha synuclein, Alpha-synuclein, isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, NACP, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid , precursor of, PARK 1, PARK 4, PARK1, PARK4, Parkinson disease familial 1, PD 1, PD1, SNCA, Snca synuclein, alpha non A4 component of amyloid precursor, Synuclein alpha, Synuclein, alpha non A4 component of amyloid precursor.

Product Description

The synuclein family members, including Alpha-synuclein (also designated NACP for non-Beta-Amyloid component) and Beta-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. Alpha-synuclein is localized to neuronal cell bodies and synapses. Alpha-synuclein was first identified as a component of Alzheimer?s disease amyloid plaques. Abnormal platelet function in Alzheimer?s disease has been demonstrated. During megakaryocytic differentiation Alpha-synuclein has been found to be upregulated, while Beta-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of Alpha-synuclein has been found in patients with early onset Parkinson?s disease.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic nitrylpeptide derived from human Alpha-synuclein around nitration site of Tyr39
• Target: Alpha-synuclein (nitro-Tyr39)

Application Notes

• Application Dilute: IHC-P(1:200-400), IHC-F(1:100-500), IF(), FCM(1ug/Test)