Phospho-BLNK (Tyr84) Polyclonal Antibody, PE-Cy5.5 Conjugated, PE/Cy5.5, Rabbit

Product Overview

• Article Name: Phospho-BLNK (Tyr84) Polyclonal Antibody, PE-Cy5.5 Conjugated, PE/Cy5.5, Rabbit
• Biozol Catalog Number: BSS-BS-9687R-PE-CY5.5
• Supplier Catalog Number: bs-9687R-PE-Cy5.5
• Alternative Catalog Number: BSS-BS-9687R-PE-CY5.5-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: PE/Cy5.5
• Alternative Names: BLNK phospho Y84, p-BLNK phospho Y84, B cell adapter containing SH2 domain protein, B cell adapter containing Src homology 2 domain protein, B cell linker, B cell linker protein, B cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, B-cell linker protein, BASH, BASH, Bca, Bca, BLNK, BLNK s, BLNK_HUMAN, Cytoplasmic adapter protein, Ly 57, Ly-57, Ly57, Lymphocyte antigen 57, Lymphocyte antigen-57, Lyw 57, Lyw-57, Lyw57, MGC111051, SLP 65, SLP65, SLP-65, Src homology 2 domain containing leukocyte protein of 65 kDa.

Product Description

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 29760
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human BLNK around the phosphorylation site of Tyr84 [EM(p-Y)VM]
• Target: Phospho-BLNK (Tyr84)

Application Notes

• Application Dilute: WB(1:300-5000)