Chromosome 21 open reading frame 70, CU070_HUMAN, Hypothetical protein LOC85395, PRED56, Uncharacterized protein C21orf70.
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimers disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf70 gene product has been provisionally designated C21orf70 pending further characterization.
