CD45 (HI30) Monoclonal Antibody, AbBy Fluor-750 Conjugated, IgG1, Clone: [HI30], BF750, Mouse

Product Overview

• Article Name: CD45 (HI30) Monoclonal Antibody, AbBy Fluor-750 Conjugated, IgG1, Clone: [HI30], BF750, Mouse
• Biozol Catalog Number: BSS-BSM-30095M-BF750
• Supplier Catalog Number: bsm-30095M-BF750
• Alternative Catalog Number: BSS-BSM-30095M-BF750-100
• Manufacturer: Bioss
• Host: Mouse
• Category: Antikörper
• Application: FC
• Species Reactivity: Human
• Conjugation: BF750
• Alternative Names: B220, CD 45, CD-45, cd45 antigen, ec3.1.3.48, CD45R, GP180, GP180, GP 180, L CA, LCA, L-CA, Leukocyte common antigen, LY5, Ly-5 glycoprotein, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, Receptor-type tyrosine-protein phosphatase C, PTPRC, PTPRC_HUMAN, SCID due to PTPRC deficiency, T200, T200 glycoprotein, T200 leukocyte common antigen, Human homolog of severe combined immunodeficiency due to PTPRC deficiency.

Product Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008].

Product Properties

• Clonality: Monoclonal
• Concentration: 1ug/ul
• Clone Designation: [HI30]
• Isotype: IgG1
• NCBI: 5788
• UniProt: P08575
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: Recombinant human CD45 protein
• Purity: Purified by Protein G.
• Target: CD45

Application Notes

• Application Dilute: FCM(1:100)