HP1 alpha Monoclonal Antibody, Biotin Conjugated, Clone: [7E3], Mouse

Product Overview

• Article Name: HP1 alpha Monoclonal Antibody, Biotin Conjugated, Clone: [7E3], Mouse
• Biozol Catalog Number: BSS-BSM-33377M-BIOTIN
• Supplier Catalog Number: bsm-33377M-Biotin
• Alternative Catalog Number: BSS-BSM-33377M-BIOTIN-100
• Manufacturer: Bioss
• Host: Mouse
• Category: Antikörper
• Application: IHC-Fr, IHC-P, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Biotin
• Alternative Names: Antigen p25, HP1-_, CBX5, CBX5_HUMAN, Chromobox homolog 5 (HP1 alpha homolog, Drosophila), Chromobox homolog 5, Chromobox protein homolog 5, Heterochromatin protein 1 alpha, Heterochromatin protein 1, Heterochromatin protein 1 homolog alpha, HP1 alpha, HP1 alpha homolog, HP1, HP1A, HP1Hs alpha.

Product Description

Component of heterochromatin that recognizes and binds histone H3 tails methylated at Lys-9 (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when Tyr-41 of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Product Properties

• Clonality: Monoclonal
• Concentration: 1ug/ul
• Clone Designation: [7E3]
• NCBI: 23468
• UniProt: P45973
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human HP1 alpha
• Target: HP1 alpha

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)