FKBP12, FKB1A_HUMAN, 12 kDa FK506-binding protein, 12 kDa FKBP, FK506 binding protein 1, FK506 binding protein 12, FK506 binding protein 1A 12kDa, FK506 binding protein 1A, FK506 binding protein T cell 12 kD, FK506-binding protein 1A, FKBP 12, FKBP 1A, FKBP-12, FKBP-1A, FKBP1, FKBP12 Exip3, FKBP12C, Immunophilin FKBP12, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP1A, PKC12, PKCI2, PPIase, PPIase FKBP1A, Protein kinase C inhibitor 2, Rotamase.
May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
