PIK3R1 Monoclonal Antibody, Biotin Conjugated, IgG1, Clone: [9B3], Mouse

Product Overview

• Article Name: PIK3R1 Monoclonal Antibody, Biotin Conjugated, IgG1, Clone: [9B3], Mouse
• Biozol Catalog Number: BSS-BSM-52219M-BIOTIN
• Supplier Catalog Number: bsm-52219M-Biotin
• Alternative Catalog Number: BSS-BSM-52219M-BIOTIN-100
• Manufacturer: Bioss
• Host: Mouse
• Category: Antikörper
• Application: IHC-Fr, IHC-P, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Biotin
• Alternative Names: Phosphatidylinositol 3-kinase regulatory subunit alpha, PIK3R1, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PIK3R1, GRB1, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha

Product Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Product Properties

• Clonality: Monoclonal
• Concentration: 1ug/ul
• Clone Designation: [9B3]
• Isotype: IgG1
• NCBI: 5295
• UniProt: P27986
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: Recombinant human PI3-kinase p85 subunit alpha protein, around 600-700aa.
• Target: PIK3R1

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)