Integrin alpha 6 Recombinant Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BSM-52265R-PE
Supplier Catalog Number:
bsm-52265R-PE
Alternative Catalog Number:
BSS-BSM-52265R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human, Mouse, Rat
Conjugation:
PE
Alternative Names:
Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD49f, ITGA6
Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.