Caspase-9 Recombinant Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: Caspase-9 Recombinant Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-52566R-BIOTIN
• Supplier Catalog Number: bsm-52566R-Biotin
• Alternative Catalog Number: BSS-BSM-52566R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IHC-Fr, IHC-P, WB
• Species Reactivity: Human, Mouse
• Conjugation: Biotin
• Alternative Names: Caspase-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP-9, APAF-3, ICE-LAP6, CASP9

Product Description

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Product Properties

• Clonality: Recombinant
• Concentration: Lot dependent
• UniProt: P55211
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: Human Caspase-9 aa 200-350
• Target: Caspase-9

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)