TFAM (16A1) Monoclonal Antibody, Clone: [16A1], Unconjugated, Rabbit

Product Overview

• Article Name: TFAM (16A1) Monoclonal Antibody, Clone: [16A1], Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-54118R
• Supplier Catalog Number: bsm-54118R
• Alternative Catalog Number: BSS-BSM-54118R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2, mtTFA, MtTF1, TCF-6, TFAM, TCF6, TCF6L2.

Product Description

Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.

Product Properties

• Clonality: Monoclonal
• Concentration: Lot Dependent
• Clone Designation: [16A1]
• NCBI: 7019
• UniProt: Q00059
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: Synthetic peptide within human mtTFA aa 50-150
• Purity: Purified by Protein A.
• Target: TFAM
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:20-100), IF(IHC-P)(1:200-400), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)