ERAP1 Monoclonal Antibody, Clone: [3H62], Unconjugated, Rabbit

Product Overview

• Article Name: ERAP1 Monoclonal Antibody, Clone: [3H62], Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-54703R
• Supplier Catalog Number: bsm-54703R
• Alternative Catalog Number: BSS-BSM-54703R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: A LAP antibody, A-LAP antibody, Adipocyte derived leucine aminopeptidase antibody, Adipocyte-derived leucine aminopeptidase antibody, ALAP antibody, Aminopeptidase PILS antibody, Aminopeptidase regulator of TNFR1 shedding antibody, APPILS antibody, ARTS 1 antibody, ARTS-1 antibody, Arts1 antibody, Endoplasmic reticulum aminopeptidase 1 antibody, Endoplasmic reticulum aminopeptidase associated with antigen processing antibody, ERAAP antibody, ERAAP1 antibody, ERAP 1 antibody, Erap1 antibody, ERAP1_HUMAN antibody, KIAA0525 antibody, kiaa0525 protein antibody, PILS AP antibody, PILS-AP antibody, PILSA antibody, PILSAP antibody, Puromycin insensitive leucyl specific aminopeptidase antibody, Puromycin-insensitive leucyl-specific aminopeptidase antibody, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody, type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody, VEGF-induced aminopeptidase antibody

Product Description

Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.

Product Properties

• Clonality: Monoclonal
• Concentration: 1ug/ul
• Clone Designation: [3H62]
• NCBI: 51752
• UniProt: Q9NZ08
• Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: Synthetic Peptide corresponding to C-terminal human ERAP1.
• Target: ERAP1

Application Notes

• Application Dilute: WB(1:300-5000)