TPT, HHG1, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5, Sonic Hedgehog.
The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity).Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity).Both activities occur in the reticulum endoplasmic (By similarity).