30 kDa adipocyte complement related protein, ACDC, ACRP30, Adipocyte, Adiponectin, Adipoq, Adipose most abundant gene transcript 1, Adipose specific collagen like factor, ADIPQTL1, ADPN, APM1, GBP28, Gelatin binding protein, Gelatin binding protein 28.
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects.
