LEF1_HUMAN, Lymphoid enhancer binding factor 1, TCF1 alpha, TCF10, Transcription factor T cell specific 1 alpha, TCF7L3.
Transcription factor that binds DNA in a sequence-specific manner.Participates in the Wnt signaling pathway.Activates transcription of target genes in the presence of CTNNB1 and EP300.PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1.