Phospho-CBL (Tyr774) Recombinant Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: Phospho-CBL (Tyr774) Recombinant Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-61354R-BIOTIN-TRIAL
• Supplier Catalog Number: bsm-61354R-Biotin
• Alternative Catalog Number: BSS-BSM-61354R-BIOTIN-20
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Biotin
• Alternative Names: Casitas B lineage lymphoma proto oncogene, CBL2, E3 ubiquitin protein ligase CBL, Oncogene CBL2, Proto oncogene c CBL, RING finger protein 55, RNF55, Signal transduction protein CBL.

Product Description

Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome.

Product Properties

• Clonality: Recombinant
• Concentration: Lot dependent
• NCBI: 867
• UniProt: P22681
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human CBL around the phosphorylation site of Y774
• Purity: Purified Polyclonal A
• Target: CBL (Tyr774)
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)