Integrin alpha 5 Recombinant Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BSM-61357R-PE
Supplier Catalog Number:
bsm-61357R-PE
Alternative Catalog Number:
BSS-BSM-61357R-PE-20,BSS-BSM-61357R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
IF, WB
Species Reactivity:
Human, Mouse, Rat
Conjugation:
PE
Alternative Names:
Integrin alpha-5, VLA-5, CD49e, ITGA5, FNRA.
Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.