Coagulation factor II, F2, Factor II, Prepro coagulation factor II, Prothrombin, prothrombin B-chain, PT, RPRGL2, serine protease, THPH1, Thrombin heavy chain.
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.