HIF1AN Recombinant Antibody, PE-Cy5.5 Conjugated, PE/Cy5.5, Rabbit

Product Overview

• Article Name: HIF1AN Recombinant Antibody, PE-Cy5.5 Conjugated, PE/Cy5.5, Rabbit
• Biozol Catalog Number: BSS-BSM-61905R-PE-CY5.5
• Supplier Catalog Number: bsm-61905R-PE-Cy5.5
• Alternative Catalog Number: BSS-BSM-61905R-PE-CY5.5-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, WB
• Species Reactivity: Human
• Conjugation: PE/Cy5.5
• Alternative Names: FIH 1, FIH1, HIF1AN.

Product Description

Hydroxylates HIF-1 alpha at Asn-803 in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins.

Product Properties

• Clonality: Recombinant
• Concentration: 1mg/ml
• NCBI: 55662
• UniProt: Q9NWT6
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human HIF 1 alpha inhibitor
• Target: HIF1AN

Application Notes

• Application Dilute: WB(1:500-2000), FCM(1ug/test)