p150 CAF1 Recombinant Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BSM-61981R-PE
Supplier Catalog Number:
bsm-61981R-PE
Alternative Catalog Number:
BSS-BSM-61981R-PE-20,BSS-BSM-61981R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
IF, WB
Species Reactivity:
Human
Conjugation:
PE
Alternative Names:
CAF, CAF1, CAF1P150, CHAF1A, DCAF1, hp15, P150.
Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.