Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-62258R
• Supplier Catalog Number: bsm-62258R
• Alternative Catalog Number: BSS-BSM-62258R-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IF, IHC-Fr, IHC-P, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: Glycogen synthase kinase-3 alpha, GSK-3 alpha, GSK3A.

Product Description

GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

Product Properties

• Clonality: Recombinant
• Concentration: Lot dependent
• NCBI: 2931
• UniProt: P49840
• Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
• Source: KLH conjugated synthetic peptide derived from human GSK3 alpha around the phosphorylation site of Y279
• Target: GSK3 A/B

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IP(1-2ug), IF(), ICC/IF(1:50-100)