ERCC8 Recombinant Antibody, APC Conjugated, Rabbit

Product Overview

• Article Name: ERCC8 Recombinant Antibody, APC Conjugated, Rabbit
• Biozol Catalog Number: BSS-BSM-62393R-APC
• Supplier Catalog Number: bsm-62393R-APC
• Alternative Catalog Number: BSS-BSM-62393R-APC-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Conjugation: APC
• Alternative Names: CKN1, CSA, ERCC8.

Product Description

Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner, ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair.

Product Properties

• Clonality: Recombinant
• Concentration: Lot dependent
• NCBI: 1161
• UniProt: Q13216
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human ERCC8
• Target: ERCC8

Application Notes

• Application Dilute: WB(1:300-5000)