BLNK Recombinant Antibody, AbBy Fluor-555 Conjugated, BF555, Rabbit

Product Overview

• Article Name: BLNK Recombinant Antibody, AbBy Fluor-555 Conjugated, BF555, Rabbit
• Biozol Catalog Number: BSS-BSM-62608R-BF555
• Supplier Catalog Number: bsm-62608R-BF555
• Alternative Catalog Number: BSS-BSM-62608R-BF555-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IF, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: BF555
• Alternative Names: AGM4, BASH, Bca, BLNK, Ly57, Lyw57, SLP65.

Product Description

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes.

Product Properties

• Clonality: Recombinant
• Concentration: Lot dependent
• NCBI: 29760
• UniProt: Q8WV28
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human BLNK
• Target: BLNK

Application Notes

• Application Dilute: WB(1:300-5000), IF()