FTO (Fat mass and obesity related protein) Antibody, IgG2a, Clone: [5-2H10], Unconjugated, Mouse, Monoclonal
Biozol Catalog Number:
BSS-BSM-70094M
Supplier Catalog Number:
bsm-70094M
Alternative Catalog Number:
BSS-BSM-70094M-100
Manufacturer:
Bioss
Host:
Mouse
Category:
Antikörper
Application:
WB
Species Reactivity:
Human, Mouse, Rat
Conjugation:
Unconjugated
Alternative Names:
AlkB homolog 9 antibody, ALKBH9 antibody, Alpha-ketoglutarate-dependent dioxygenase FTO antibody, AW743446 antibody, Fat mass and obesity-associated protein antibody, FATSO, MOUSE, HOMOLOG OF antibody, Fto antibody, FTO_HUMAN antibody, GDFD antibody, KIAA1752 antibody, mKIAA1752 antibody, Protein fatso antibody
The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008). Deletion analysis of FTO gene in mice showed that FTO is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009).