Lamin A/C Antibody, IgG1, Clone: [4C4], Unconjugated, Mouse, Monoclonal

Product Overview

• Article Name: Lamin A/C Antibody, IgG1, Clone: [4C4], Unconjugated, Mouse, Monoclonal
• Biozol Catalog Number: BSS-BSM-70138M
• Supplier Catalog Number: bsm-70138M
• Alternative Catalog Number: BSS-BSM-70138M-100
• Manufacturer: Bioss
• Host: Mouse
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: 70 kDa lamin antibody, Cardiomyopathy dilated 1A (autosomal dominant) antibody, CDCD1 antibody, CDDC antibody, CMD1A antibody, CMT2B1 antibody, EMD2 antibody, FPL antibody, FPLD antibody, FPLD2 antibody, HGPS antibody, IDC antibody, Lamin A antibody, Lamin A/C antibody, Lamin A/C like 1 antibody, Lamin antibody, Lamin C antibody, Lamin-A/C antibody, LDP1 antibody, LFP antibody, LGMD1B antibody, Limb girdle muscular dystrophy 1B (autosomal dominant) antibody, LMN 1 antibody, LMN A antibody, LMN C antibody, LMN1 antibody, LMNA antibody, LMNA_HUMAN antibody, LMNC antibody, LMNL1 antibody, Prelamin A/C antibody, PRO1 antibody, Renal carcinoma antigen NY REN 32 antibody, Renal carcinoma antigen NY-REN-32 antibody, Renal carcinoma antigen NYREN32 antibody

Product Description

Lamins A and C are nuclear structural proteins that are part of the intermediate filament family and coded for by the same gene (LMNA). Lamins A and C are nearly identical except for their carboxy termini (McKeon et al., 1986). Mutations in the gene encoding lamins A/C have been shown to cause a variety of diseases including autosomal dominant Emery-Dreifuss muscular dystrophy (Bonne et al., 1995), autosomal dominant limbgirdle muscular dystrophy (Muchir et al., 2000) and Charcot-Marie-Tooth disorder type 2 (De Sandre-Giavonnoli et al., 2002).

Product Properties

• Clonality: Monoclonal
• Concentration: Lot Dependent
• Clone Designation: [4C4]
• Isotype: IgG1
• NCBI: 4000
• UniProt: P02545
• Buffer: PBS + 10 mM NaN3.
• Source: Recombinant full length human lamin C expressed in and purified from E. Coli.
• Target: Lamin A/C

Application Notes

• Application Dilute: WB(1:300-5000), IHC()