DAUD I6 antibody, DAUDI6 antibody, H 2RIIBP antibody, H2RIIBP antibody, MGC1831 antibody, MHC class I promoter binding protein antibody, NR2B2 antibody, nuclear receptor subfamily 2 group B member 2 antibody, RCoR 1 antibody, RCoR1 antibody, Retinoic acid receptor RXR beta antibody, RXR beta antibody, RXRB antibody, RXRbeta antibody
Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRalpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Source:
Synthetic peptide corresponding to amino acid residues from the mouse retinoid X receptor, beta- isotype, conjugated to keyhole limpet hemocyanin (KLH).
Target:
Retinoid X Receptor, ß-Isotype
Application Dilute:
WB(1:300-5000)
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